Genome Sequencing

Toward
Final-Gen Sequencing

The most comprehensive view of the genome to realize the future of precision medicine

The Scalability to Deliver the $100,
1-Hour Genome and Beyond...

Powering the Precision Medicine Knowledgebase

Full interpretation of the genome requires a comprehensive knowedgebase of millions of genomes, and sequencing cost remains the significant barrier

Enabling Universal Access to the Genome

Simple, fast, affordable sequencing will usher in the era where your genome predicts your risks for disease and provides choices for prevention or treatment, guiding your health decisions

Envisioning the Final-Generation Sequencing Platform for All Applications

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Whole Genome
Sequencing

Targeted
Sequencing

Metagenomic
Sequencing

RNA

Direct Reading of
RNA

Transcriptome
Profiling

Small RNA Profiling
(miRNA)

PROTEIN

Direct Reading of
Epigenetic Marks

Methylation
Sequencing

DNA Damage
Detection

Key Attributes

N01.

FINAL-GENERATION SEQUENCING

The Roswell technology roadmap addresses all the fundamental elements required to realize the ultimate precision medicine genome

Simple

Single-molecule chemistry enables simple sample prep for plug-and-play operation anywhere

Comprehensive

Long-read length, resolution for epigenetic markers, and access to difficult-to-sequence regions, unlock a complete view of the genome

Accessible

Miniaturized, low-cost devices deployable in the community will expand access beyond centralized labs

Low Cost

The Roswell ME Chip scalability drives continual cost reductions to broadly expand the use of sequencing for precision medicine

Accurate

Information rich electrical measurements enable a high resolution view of both sequence and epigenetics

Fast

High-throughput, real-time electrical readout provides the ultimate in speed, enabling sequencing in minutes and not days

The Roswell Precision Medicine is Delivering

DIGITIZING SEQUENCING

Polymerase

Meets the Molecular Electronics Chip

Ultimate Scalability

Going
On-Chip

On chip integration leverages the multi-trillion-dollar investment in the semiconductor industry for the ultimate in scalability and low-cost manufacturing

Access for All

Low-Cost Instruments, Simple Workflows

The power of a polymerase on-chip frees sequencing from slow, costly central labs to deliver precision wellness to the individual

Digitizing Biology

The Path
to Realizing Precision Medicine

Just as the first microprocessor chip digitized information, the first molecular microchip is digitizing biology to create the knowledgebase and access needed to realize precision medicine

Dr. George Church

World-renowned geneticist and professor, Harvard University and MIT, & Roswell Scientific Advisory Board Member

With Roswell we see the sequencing revolution continuing by another factor of ten — combined with a nearly insatiable, growing set of applications and appetite for reading DNA. We hope this moves us ever closer to equitable access to precision medicine for all.

Dr. George Church

World-renowned geneticist and professor, Harvard University and MIT, & Roswell Scientific Advisory Board Member

James M. Tour, Ph.D.

Professor of Chemistry, Rice University & Roswell Scientific Advisory Board Member

What Roswell is bringing to the world is the $100 genome that can scale rapidly and also deliver Exabyte data storage.